Dehydrated Human Amnion Chorion Membrane as Treatment for Pediatric Burns

PURION® Processed Dehydrated Human Amnion/Chorion Membrane Allografts

Dehydrated Human Amnion/Chorion Membrane (dHACM) Allografts as a Therapy for Orthopedic Tissue Repair

The amniotic membrane is a placental tissue that supports the development of the fetus during pregnancy. It is composed of extracellular matrix components such as collagen, fibronectin, and laminin, and contains many different growth factors and cytokines. Amniotic membrane can be PURION Processed to produce dehydrated human amnion/chorion membrane (dHACM, Epifix, Amniofix; MiMedx Group Inc.) a...

Dehydrated Human Amnion/Chorion Membrane Allograft Promotes Cardiac Repair Following Myocardial Infarctions

Acute myocardial infarction (MI), more commonly known as heart attack, is a major consequence of cardiovascular disease and a leading cause of morbidity and mortality worldwide. Acute MI occurs when coronary occlusion causes diminished blood supply to the cardiac tissue, and myocardial ischemia results in irreversible damage or cell death [1]. Reperfusion therapy in the form of primary percutan...

Dehydrated human amnion/chorion membrane regulates stem cell activity in vitro

Human-derived placental tissues have been shown in randomized clinical trials to be effective for healing chronic wounds, and have also demonstrated the ability to recruit stem cells to the wound site in vitro and in vivo. In this study, PURION(®) Processed dehydrated human amnion/chorion membrane allografts (dHACM, EpiFix(®) , MiMedx Group, Marietta, GA) were evaluated for their ability to alt...

Intra-articular injection of micronized dehydrated human amnion/chorion membrane attenuates osteoarthritis development

INTRODUCTION Micronized dehydrated human amnion/chorion membrane (μ-dHACM) is derived from donated human placentae and has anti-inflammatory, low immunogenic and anti-fibrotic properties. The objective of this study was to quantitatively assess the efficacy of μ-dHACM as a disease modifying intervention in a rat model of osteoarthritis (OA). It was hypothesized that intra-articular injection of...